Medicinal Natural Products
| Автор(ы): | Dewick Paul M.
06.10.2007
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| Год изд.: | 2002 |
| Описание: | "Не читал. По названию можно сказать, что книга про "медицинские натуральные продукты", что уже противоречит само себе. Значит, вам нужно прочитать эту книгу и прислать хоть какую-нибудь рецензию, а то по оглавлению я тоже ни черта не понял. Может продукты какие действительно классные." |
| Оглавление: |
Обложка книги.
The Subject [1] The Aim [1] The Approach [2] The Topics [2] Be Selective [2] To Learn, or to Understand? [3] Conventions Regarding Acids, Bases, and Ions [3] Nomenclature [3] Some Common Abbreviations [4] Further Reading [4] 2 SECONDARY METABOLISM: THE BUILDING BLOCKS AND CONSTRUCTION ECHANISMS [7] Primary and Secondary Metabolism [7] The Building Blocks [8] The Construction Mechanisms [12] Alkylation Reactions: Nucleophilic Substitution [12] Alkylation Reactions: Electrophilic Addition [13] Wagner-Meerwein Rearrangements [15] Aldol and Claisen Reactions [15] Schiff Base Formation and the Mannich Reaction [18] Transamination [20] Decarboxylation Reactions [20] Oxidation and Reduction Reactions [24] Dehydrogenases [24] Oxidases [25] Mono-oxygenases [25] Dioxygenases [27] Amine Oxidases [28] Baeyer-Villiger Oxidations [28] Phenolic Oxidative Coupling [28] Glycosylation Reactions [29] Some Vitamins Associated with the Construction Mechanisms [30] Vitamin B1, Vitamin B2, Vitamin B5, Vitamin B6, Vitamin B12, Vitamin H Further Reading [33] 3 THE ACETATE PATHWAY: FATTY ACIDS AND POLYKETIDES [35] Saturated Fatty Acids [36] Unsaturated Fatty Acids [40] Fixed Oils and Fats, Evening Primrose Oil Acetylenic Fatty Acids [47] Branched-Chain Fatty Acids [48] Prostaglandins [51] Prostaglandins Isoprostanes Thromboxanes [58] Thromboxanes Leukotrienes [58] Leukotrienes Aromatic Polyketides [60] Cyclization: Simple Phenols [61] Structural Modifications: Anthraquinones [63] Senna, Cascara, Frangula, Allied Drugs, Hypericum/St John's Wort C-Alkylation Reactions [72] Mycophenolic Acid, Khellin and Cromoglicate Phenolic Oxidative Coupling [76] Griseofulvin Oxidative Cleavage of Aromatic Rings [78] Starter Groups Other Than Acetate [79] Poison Ivy and Poison Oak, Aflatoxins, Cannabis, Tetracyclines, Anthracycline Antibiotics Macrolides and Polyethers [92] Extender Groups other than Malonate [92] Macrolide Antibiotics, Avermectins, Polyene Antifungals, Tacrolimus and Sirolimus, Ansa Macrolides Cyclization Through Diels-Alder Reactions [111] Mevastatin and other Statins Genetic Manipulation of the Acetate Pathway [114] Further Reading [117] 4 THE SHIKIMATE PATHWAY: AROMATIC AMINO ACIDS AND PHENYLPROPANOIDS [121] Aromatic Amino Acids and Simple Benzoic Acids [121] Folic Acid (Vitamin B9), Chloramphenicol Cinnamic Acids [130] Lignans and Lignin [132] Podophyllum Phenylpropenes [135] Volatile Oils Containing Principally Aromatic Compounds Benzoic Acids from CeC3 Compounds [141] Coumarins [142] Dicoumarol and Warfarin, Psoralens Styrylpyrones [147] Kava Flavonoids and Stilbenes [149] Flavonolignans [151] Silybum marianum Isoflavonoids [154] Phyto-oestrogens, Derris and Lonchocarpus Terpenoid Quinones [158] Vitamin E, Vitamin К Further Reading [164] 5 THE MEVALONATE AND DEOXYXYLULOSE PHOSPHATE PATHWAYS: TERPENOIDS AND STEROIDS [167] Hemiterpenes (C(?)) [172] Monoterpenes (С(?)) [172] Volatile Oils Containing Principally Terpenoid Compounds Irregular Monoterpenes [186] Pyrethrins Iridoids (С(?)) [187] Valerian Sesquiterpenes (Cis) [191] Feverfew, Chamomile and Matricaria, Artemisia annua and Artemisinin, Gossypol, Trichothecenes Diterpenes (C2(?)) [203] Taxus brevifolia and Taxol (Paclitaxel), Ginkgo biloba, Forskolin Sesterterpenes (C(?)) [212] Triterpenes (C3(?)) [212] Triterpenoid Saponins [219] Liquorice, Quillaia, Ginseng Modified Triterpenoids [225] Tetraterpenes (C(?)) [226] Vitamin A Higher Terpenoids [231] Steroids [232] Stereochemistry [232] Cholesterol [233] Cholesterol Steroidal Saponins [237] Dioscorea, Fenugreek, Sisal, Sarsaparilla, Yucca Cardioactive Glycosides [241] Digitalis purpurea, Digitalis lanata, Strophanthus, Convallaria, Squill, Toxic Plants Phytosterols [252] Soya Bean Sterols, Fusidic Acid Vitamin D [257] Vitamin D Bile Acids [260] Bile Acids Adrenocortical Hormones/Corticosteroids [262] Semi-Synthesis of Corticosteroids [264] Corticosteroid Drugs Progestogens [267] Progestogen Drugs Oestrogens [272] Oestrogen Drugs, Aromatase Inhibitors, Oestrogen Receptor Antagonists Androgens [282] Androgen Drugs Further Reading [285] 6 ALKALOIDS [291] Alkaloids Derived from Ornithine [292] Pyrrolidine and Tropane Alkaloids [292] Belladonna, Stramonium, Hyosycamus, Duboisia, Allied Drugs, Hyoscyamine, Hyoscine and Atropine, Coca Pyrrolizidine Alkaloids [305] Alkaloids Derived from Lysine [307] Piperidine Alkaloids [307] Lobelia [308] Quinolizidine Alkaloids [309] Indolizidine Alkaloids [310] Alkaloids Derived from Nicotinic Acid [311] Pyridine Alkaloids [311] Vitamin B3, Tobacco, Areca Alkaloids Derived from Tyrosine [315] Phenylethylamines and Simple Tetrahydroisoquinoline Alkaloids [315] Catecholamines, Areca, Lophophora, Curare Modified Benzyltetrahydroisoquinoline Alkaloids [327] Opium [329] Phenethylisoquinoline Alkaloids [341] Colchicum Terpenoid Tetrahydroisoquinoline Alkaloids [343] Ipecacuanha Amaryllidaceae Alkaloids [345] Galanthamine Alkaloids Derived from Tryptophan [346] Simple Indole Alkaloids [347] 5-Hydroxytryptamine (Serotonin), Psilocybe Simple p-Carboline Alkaloids [349] Terpenoid Indole Alkaloids [350] Rauwolfia, Catharanthus, Iboga, Nux-vomica, Ellipticine Quinoline Alkaloids [359] Cinchona, Camptothecin Pyrroloindole Alkaloids [365] Physostigma Ergot Alkaloids [368] Ergot, Morning Glories Alkaloids Derived from Anthranilic Acid [376] Quinazoline Alkaloids [377] Quinoline and Acridine Alkaloids [377] Alkaloids Derived from Histidine [379] Imidazole Alkaloids [379] Pilocarpus Alkaloids Derived by Animation Reactions [381] Acetate-derived Alkaloids [381] Conium maculatum Phenylalanine-derived Alkaloids [382] Ephedra, Khat Terpenoid Alkaloids [385] Steroidal Alkaloids [388] Solarium Alkaloids Purine Alkaloids [394] Caffeine, Theobromine, and Theophylline, Coffee, Tea, Cola, Cocoa, Mate Tea, Guarana Saxitoxin and Tetrodotoxin [396] Saxitoxin, Tetrodotoxin Further Reading [398] 7 PEPTIDES, PROTEINS, AND OTHER AMINO ACID DERIVATIVES [405] Peptides and Proteins [405] Ribosomal Peptide Biosynthesis [407] Peptide Hormones [410] Thyroid Hormones [410] Thyroxine, Calcitonin Hypothalamic Hormones [411] Thyrotrophin-Releasing Hormone, Luteinizing Hormone-Releasing Hormone, Growth Hormone-Releasing Hormone/Factor, Somatostatin Anterior Pituitary Hormones [413] Corticotropin, Growth Hormone, Prolactin, Gonadotrophins Posterior Pituitary Hormones [413] Oxytocin, Vasopressin Pancreatic Hormones [416] Insulin, Glucagon Interferons [417] Interferons Opioid Peptides [417] Enzymes [419] Nonribosomal Peptide Biosynthesis [421] Peptide Antibiotics [423] Cycloserine, Polymyxins, Bacitracins, Tyrothricin and Gramicidins, Capreomycin, Vancomycin and Teicoplanin, Bleomycin, Cyclosporins, Streptogramins, Dactinomycin Peptide Toxins [433] Death Cap (Amanita phalloides), Ricin, Botulinum Toxin, Microcystins, Snake Venoms Modified Peptides: Penicillins, Cephalosporins, and Other p-Lactams [422] Penicillins [422] Penicillins Cephalosporins [444] Cephalosporins, Cephamycins, Carbacephems Other P-Lactams [450] Clavulanic Acid, Carbapenems, Monobactams Cyanogenic Glycosides [455] Glucosinolates [457] Cysteine Sulphoxides [460] Garlic Further Reading [461] 8 CARBOHYDRATES [465] Monosaccharides [465] Oligosaccharides [469] Monosaccharides and Disaccharides, Vitamin С Polysaccharides [473] Polysaccharides Aminosugars [477] Aminoglycosides [478] Aminoglycoside Antibiotics, Streptamine-containing Antibiotics, 2-Deoxystreptamine-containing Antibiotics, Acarbose, Lincomycin and Clindamycin Further Reading [486] Index [487] |
| Формат: | djvu |
| Размер: | 9029044 байт |
| Язык: | ENG |
| Рейтинг: |
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| Открыть: | Ссылка (RU) |