Viral Vectors: Basic Science and Gene Therapy
| Автор(ы): | Cid-Arregui Angel
06.10.2007
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| Год изд.: | 2000 |
| Описание: | This major new volume provides in-depth descriptions of the most relevant viral vector systems currently in use and describes the recent important developments in this field. 37 chapters provide updated methods to prepare the vectors as well as information on their applications to cell biology, neurobiology, gene therapy and more. Ну, а если по-русски: Книга затрагивает вопросы внедрения генов в вектор - молекулу ДНК, способную к автономной репликации и включающую в себя чужеродную ДНК. Рассказывается о свойствах маркеров, многопийности генов, регулируемой экспрессии. |
| Оглавление: |
Обложка книги.
Introduction to Part I [3] FAMILY: PARVOVIRIDAE. GENUS: DEPENDOVIRUS (ADENO-ASSOCIATED VIRUSES [AAV]) 1 Gene Transfer with Adeno-Associated Virus Vectors [11] A. Srivastava 2 Strategies for Production of Adeno-Associated Virus Vectors [27] D. Grimm and].A. Kleinschmidt 3 Production and Purification Systems for Recombinant Adeno-Associated Virus Type-2 Vectors [59] J.E. Conway, K. Chesnut, I. Zolotukhin, C. apRhys, N. Muzyczka, S. Zolotukhin, and B.J. Byrne 4 Utility of rAAV for Gene Transfer into Neurons and Other Highly Differentiated Cells [75] E.E Terwilliger 5 Adeno-Associated Virus Vectors for Genetic Immunization [85] W.C. Manning and X. Paliard FAMILY: PARVOVIRIDAE. GENUS: AUTONOMOUS PARVOVIRUSES 6 Autonomous Parvovirus Vectors [97] J.J. Cornells, A. Haag, C. Kornfeld, G. Balboni, A. Y. Dege, B. Neeb, C. Dinsart, and]. Rommelaere FAMILY: ADENOVIRIDAE. GENUS: MASTADENOVIRUS (MAMMALIAN ADENOVIRUSES) 7 Molecular Biology of Adenovirus Gene Therapy Vectors [119] M.J. Imperiale 8 Helper-Dependent Adenoviral Vectors: A New Generation of Gene Delivery Vehicles [129] M.A. Morsy and L. Chen 9 Generation of Multiply Deleted Adenovirus Vectors that are Helper Virus Independent [139] A. Amalfitano 10 Adenovirus-Mediated Gene Transfer: In Vivo Persistence of Transduced Cells and Control of Transgene Expression [153] R. Rooke, L. Grave, M. Christ, M. Lusky, A. I. Michou, andM. Mehtali 11 Molecular Conjugate Vectors [171] P. Schwarzenberger andJ.K. Kolls FAMILY: HERPESVIRIDAE. GENUS: ALPHASIMPLEXVIRUS (HERPES SIMPLEX VIRUS) 12 Construction of Defective Herpes Simplex Recombinant Vectors and Helper-Dependent Amplicons [193] A. Cid'Arregui andF. Lim 13 Gene Transfer Using Helper Virus-Free Herpes Simplex Virus Type 1 Amplicon and Hybrid Amplicon Vectors [211] Y. Saeki and C. Fraefel 14 Stable Gene Transfer Using Hybrid Herpes Simplex-Epstein-Barr Virus Amplicon Vectors [235] T.A. Stavropoubs and C.A. Strathdee 15 Herpesvirus/Retrovirus Chimeras for Gene Delivery [251] C. Zaupa andA.L. Epstein 16 Gene Transfer into Brain Slices from Mouse Embryos Using Herpes Simplex Amplicons [265] A. Cid-Arregui and W. Haubensak 17 Gene Transfer into Cultured Postimplantation Mouse Embryos Using Herpes Simplex Amplicons [277] B. Oback, A. Cid-Arregui, and W.B. Huttner 18 The Use of Herpes Simplex Vectors to Study Alzheimer's Disease Neurodegeneration [295] R.L. Neve, D.L. McPhie, andS. Bursztajn FAMILY: HERPESVIRIDAE. SUBFAMILY: GAMMAHERPESVIRINAE. GENUS: RHADINOVIRUS 19 Gamma-2-Herpesvirus Vectors for Investigation of Viral Pathogenesis and Experimental Gene Transfer [305] S.M. Duboise and]. U. Jung FAMILY: HERPESVIRIDAE. SUBFAMILY: GAMMAHERPESVIRINAE. GENUS: EPSTEIN-BARR VIRUS 20 Application of Epstein-Barr Virus and its Genetic Elements to Gene Therapy [325] O. Mazda FAMILY: POXVIRIDAE. SUBFAMILY: ENTOMOPOXVIRINAE. GENUS: ENTOMOPOXVIRUS В 21 Entomopoxvirus Vectors [341] A.L. Bawden, Y. Li, K.J. Glass berg, and R. W. Moyer FAMILY: BACULOVIRIDAE. GENUS: NUCLEOPOLYHEDROVIRUS (BACULOVIRUS) 22 High-Efficiency Transduction of Mammalian Cells Using Baculovirus: Practical Aspects [359] F.M. Boyceand E.A. Franco PART II: RNA VIRUS VECTORS Introduction to Part II [371] FAMILY: RETROVIRIDAE. GENUS: ONCOVIRINAE (MLV) 23 Strategies and Mechanisms for Retrovirus Retargeting [379] K. Bupp and M. Roth 24 Efficient Production of VSV-G-Pseudotyped Retrovirus Vectors Using Stable Packaging Cell Lines [401] H. Iba, T.Arai, and M. Ui 25 Utility of Scaffold Attachment Regions for Enhanced Retroviral Vector Expression in Human Hematopoietic Cells [413] I. Plavec and M. Agarwal 26 Kinetics of Transduction Using Retroviral Vectors: Enhancement by Complex Formation with Cationic Liposomes [431] C. Porter 27 Retrovirally Mediated Genetic Marking of Murine and Human Hematopoietic Repopulating Cells [447] A. Bernad, E Varas, M. Ramirez, J. C. Segovia, G. Guenechea, J. Barquinero, and J.A. Bueren 28 Towards the Genetic Manipulation of the Hematopoietic System: Tumor-Specific Gene Therapy Strategies [467] C. Cobaleda and I. Sdnchez-Garria FAMILY: RETROVIRIDAE. GENUS: LENTIVIRINAE (HIV) 29 Cellular Transduction by Lentiviral Vectors [485] R.E. Sutton FAMILY: RETROVIRIDAE. GENUS: SPUMAVIRINAE (FOAMY VIRUSES) 30 Foamy Viruses: Molecular Features and Therapeutic Potential [503] C.L Hill and M.O. McClure 31 Aspects of Foamy Virus Vectors: Host Range and Replication-Competent Vectors [515] D. Lindemann, M. Heinkelein, and A. Rethwilm FAMILY: ORTHOMYXOVIRIDAE. GENUS: INFLUENZA VIRUS 32 Transfectant Influenza Viruses as Vaccine Vectors [525] A. Garda-Sastre FAMILY: PICORNAVIRIDAE. GENUS: ENTEROVIRUS (POLIOVIRUS) 33 Picornaviruses as Tools for Antigen Delivery [543] S. Mueller and E. Wimmer FAMILY: TOGAVIRIDAE. GENUS: ALPHAVIRUS (SEMLIKI FOREST VIRUS, SINDBIS VIRUS) 34 Strategies and Applications of Alphavirus Vectors in Gene Therapy [565] S.M. Smith and K.-T. Jeang 35 Efficient Expression of Proteins with Recombinant Alphaviruses [575] A. Cid-Arregui, N. Morales-Peza, V. Juarez, M.J. Garda-Iglesias, and A. Garcia-Carrancd PART III. GENERAL ISSUES 36 Gene Therapy Using Viral Vectors: Strategy and Design Issues [597] P.A. Lazo and M. Yunta 37 Biosafety Recommendations for Working with Viral Vectors [609] A. Cid-Arregui and V Juarez INDEX [619] |
| Формат: | djvu |
| Размер: | 9103519 байт |
| Язык: | ENG |
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| Открыть: | Ссылка (RU) |